[GAMEPLAY] Unresponsive Mouse Clicks

So, for the last 2 weeks or so, there has been a consistent bug with mouse clicks failing to register in game. I personally experience this issue every game, but from constantly asking if others are suffering from the issue in my games, I've found that usually at least one other person suffers from it throughout each game, up to four people who can barely even play due to this issue. The most frustrating aspect is the fact that it seems to be randomized and unpredictable. The time frame of unresponsiveness can go anywhere from ~1/2 a second to an impossibly infuriating 4 seconds of inactivity. During the unresponsiveness you still have the ability to cast spells and summoners, and no one else in the game is affected. Gameplay proceeds as normal, there is no fps drop or ping spike, no visual difference, but your character continues the last issued command, whether it was walking towards baron, auto attacking a minion, trying to ward, etc. As you might imagine this bug is a large inconvenience and I have seen little to no attention drawn to this. This is the first bug I've reported as it's the first I've found that complete inhibits my ability to play the game, so let me know if there's anything else you need to know. Thanks for listening,

-Xurrender