Help!!! Interfering with gameplay

Hey, I recently have gotten back into playing league and recently I've noticed there has been this weird bug with my game and its interfering with the game. It costed me numerous games/kills. Randomly the cursor animation when you left click turns red instead of green and my champion cannot be controlled and runs off and attacks nearby hostiles. I have found a fix to this problem but, it is inefficient and I have to do it so often since the bug happens 4-5 times a game. Please help me find a better solution. Thanks