Random Game Crashes

In the past hours, I did updates on malware, windows, and my video cards. Before this, they were out of date. As soon as there were all complete, I decided to launch league. Opening it up was no problem, as well as getting into champ select. However, when the client itself opened up, my game crashed about a minute it. I had no idea why, so I entered my game again after reconnecting. Unfortunately, it crashed again a minute after being in the client again. I do get a "Splat" thing or whatever, but that doesn't really do anything.

HELP