Bug

Hello. I play lol often, but sometimes I a get really anoying bug. Game started, all good, but than suddenly (for example) in 26 min i get bug. If i click, it has red colour, can not buy items, my spells are like "smart cast" even i do not have it setted, when I start hit enemy or minion - can not stop. Other game - no bug, all good. Do not understand it...please help me to solve it.