Game crashes When I try to run anything else

It started after that update when aram can get key frags. (not sure that patch number) But after that patch, my league is pretty much crashing everytime I try to open chrome or anything else like skype...It doesn't always crash but when league is opened. I can't even click anything else outside the game window. When sometimes I can click the chrome, my game just closes.

Also, after character select, the loading screen sometimes doesn't start. It even closes itself sometimes. Its so random. I dont have lolreplay or anything like that. I tried uninstalling league delete everything and reinstalled it, still has that problem. There is no specific action that i do that will trigger this. its just so random sometimes. Cant run anything else other than league... No Chrome, no Words, No explorer, etc.

Please helppp~~~~ T_T

Thanks! Zinna