Rune Page is glitching always [CLIENT]

Whenever im in champ select i have 2 rune pages 1 is for my main and other is for other champs so whenever i try to edit those runes and save it doesnt save when i click close on the rune page it says again do you want to save so i click yes again then i click close the same thing shows up until the game starts then when the game begins im my main's runes. Please reply a fix as soon as possible. Thank You :)