[GAMEPLAY] Huge BUG - unable to click any UI button, move, recall and tons of other problems

I've been searching for fix or something with no success.

To better describe this HUGE bug/problem/glitch I will add symptoms in here:

Once this bug happens, you can't click on any UI element in the game including abilities (including +button when you level up), minimap, pings, options menu, your hero's details, tips, ...

Hero is in some kind of "harcore-attack" mode so once this bug occurs and you are for example in a fight, you can't move out of it because your hero just attacks nearest enemy with basic attacks (and you die, of course)

You can use your abilities using your keyboard, BUT you can't control them: for example playing with Cho'Gath you use Q but you can't point to a place where you want your spell to land (funny that every hero just fires spell to the nearest enemy so you can use Brand's ulti but he fires it to the nearest enemy, if there is some enemy around)

Your cursor changes to red instead of green and it stays that way untli you reconnect

You can't recall or use D&F abilities

You can't use spacebar to center view on your hero

You CAN open shop but you can't buy anything (that's interesting when no other UI buttons do not work, but the Shop button works) - and once you open the shop, you can't close it (obviously)

You CAN type in chat - so if you are lucky and you somehow manage to get your hero to base you can stand there and chat with fellow teammates (yeah, that's "cool")

You even can't quit the game properly as ESC is not working (nor the Options Menu button above the minimap) so you had to press CMD + Q so dialog opens asking you if you want to leave the game BUT you can't click on anything so you need to press CMD + Q again to hardquit, then you need to reconnect and everything is back to normal

Once you reconnect, it takes sometimes just 15 seconds and the bug occurs again, which is very very frustrating and sometimes it does not happen again in that particular game

I tried to find what can cause these problems - like closing all applications, not using ingame chat at all, trying different heroes, reinstalling LoL etc. And it always happened. What is interesting is that I played for example 3 games in row without a problem and bam - 4th game and I died 3 times thanks to this glitch.

My next move will be to try it on PC and on older Mac and try to find out if it's maybe not connected to my profile, somewhat.

It never happened BEFORE new 5.5 patch. Never. Really.

It's really strange as for example my teammates have also Macs and nobody had this problem.