[Gameplay] Sudden loss of control

What happens:

I will be playing a game (so far it does not seem to matter what champion i am playing on) and suddenly I will lose control over various aspects of my champions. So far this includes no use of left/right click or space bar (to recenter the screen) or the escape key.

This seems to happen randomly, i have had it happen in the first minute, or 10-15minutes in. This seems to happen independent of champion. As far as i can tell, there is nothing "triggering" this glitch, so I don't know how to reproduce it.

I don't think it occurred pre-5.7. The only thing that seems to fix it is closing and re-opening the game.

Also, it may be important to note that I am playing on a mac client.

I am posting this to a) find out if anyone else is experiencing this glitch b) bring it to Riots attention.

It is EXTREMELY frustrating when it happens.