Macros

Hi Riot!, Ive been having some issues with my mouse macros currently. I have a Razer Deathadder (normal). I use my macros for my Mastery Taunt and ward. I havent been able to use the macros due to the fact that it doesnt work. i have no idea if its the client or my mouse. I can usually change it on the client but unable to change it in game. Help would be greatly appreciated. BruceyDuicey