Riot your game doesn't work sometimes.

So I'm having this issue where I'll try to use an ability and it doesn't activate. I can click on my HUD to activate the ability, but everyone who has played League before knows this is not really an option. This has happened to me multiple times where my keyboard won't let me use my abilities, but I can still type perfectly fine. Riot, could you kindly fix your game so I can actually play pllllzzzz kthxbai.