Game Unplayable - Mouse and Keyboard is not detected in the game

Hello,

I've been having this very big issue lately which makes the entire game unplayable. I have played alot of ranked games today before I left for a birthday party. 6-7 hours later, I returned and decided to do 1 last game before bed. This time, I start up ranked, get into champion select, pick my champion, locks in the right runes and summoners. The game starts, once I enter the game I notice that the white mouse cursor is on the middle of the monitor and not the league game cursor. I alt tabbed out and into the game to fix it like it usually works. However, nothing happens. I can't move, I can't click on anything at all. Eventho the game is on as primary, nothing happens. I tried to reconnect multiple times as I didnt' want to let down my team. I googled up the problem without finding any good solutions for it. I tried out the guide riot had for missing mouse and keyboards, but nothing changed. I have deleted the recommended config files in the league of legends folder. Still nothing. I have countless times tried to get into practice game, and test it out. Every little change I did. But nothing works at all. This is getting really frustrating and I really hope someone can come up with a solid fix/solution for this problem.

Also, I dont understand why the game tab itself when it starts up. It just feels like it never are able to toggle it back to primary again eventho its set as primary active window.