Summoner Spells Non-functional (sometimes)

I've been playing League of Legends for awhile now, and I've always had an issue where at the beginning of a match, my Summoner Spells would work flawlessly. For some reason after they come off of a CD, they do not work right away. After spamming and/or waiting and trying again shortly afterwards, then it works. It has caused countless deaths and team fight losses due do this bug. I have taken a few precautions in terms of fixing the potential problem on my end. Changing the keyboard (3 times), re-assigning the spells to another keybind, clicking manually with the mouse (and changing the mouse as well), and re-installing the game.

My guess is that for some odd reason, my clients internal timer is off. It's the only conclusion I have been able to come up with. It's very frustrating when i'm trying to save a fellow teammates life with a last second heal , or get away with a flash , only to realize it didn't activate when I decided to use it.

I've played with this bug for quite some time, and have checked on and off off the forums for anybody with similar problems. I am really hoping there is a suggestion or a fix for this, because i really do enjoy the game, i just wish this part of it worked properly for me. Any suggestions or fixes that anybody else has encountered? It would be greatly appreciated. Fellow Summoner,

InfamousTrixsta