It's not confirmed. Anytime a dev responds on the matter, they don't give a hard "No,", they just give a tongue in cheek response like "Wait, really?" or "Wow, that WOULD be interesting".
I think it's pretty obvious that she is Kassadin's daughter, but that bit of info isn't just trivia. The loss of his daughter basically drove Kassadin insane and inspired his mission to fight the Void, by any means necessary. If it turned out that his daughter was alive this whole time, would everything he's sacrificed fighting the Void have been worth it? Is he even capable of living a normal life now? Discovering his daughter is a huge moment in Kassadin's story that can't just be confirmed offhandedly.
We're likely waiting for a short story or something along that line to confirm it.