League of Legends MMORPG
I feel like the lore and world of League of Legends would make a great MMORPG game likewise to World of Warcraft. And you would choose different factions like Noxus, Demacia, Ionia, Bandle City, Shadow Isles, and etc. The main town/hub would be something like Bilgewater (could be changed later on) so it could be a place to take up quests. Speaking of quests you could take them from champions like Darius at Noxus or do something for the League of Assassins. Plus with Factions in you can do events like the classic Noxus vs Demacia. Well, this is all I have so far so keep your ideas below :^)