The Single Downvote Problem
This forum has come a long ways. But it is still very vulnerable to trolls. The most obvious to me is that a single downvote on a brand new thread can knock it out of the list of "Hot" threads before anyone else has a chance to read it. Hot is default and by far the most commonly used method for sorting. I have experimented with this several times with my own threads and threads I felt were legitimately worthy of a downvote and come up with the same results. This is extremely easy to abuse. There is a good chance that a single downvote will kill a new thread.
I am not sure how this would be fixed. It would be nice if threads had to be opened again before they could be up/down voted, but that doesn't actually address this issue. Perhaps new threads could be given a short timed grace period before they get delisted from Hot (unless they hit a certain threshold of downvotes). I can't tell if there is one now, but if there is then it is very short. Just an idea.