Hopefully with the new client they will be able to detect and kick out those using third party software to Auto-farm IP as Bots.
Maybe give the player a prompt "League client has detected a third party app "App name here etc" that may interfere with the League client, Kindly close this app or you will be kicked from the current match making lobby. Thank you."
Players will have 15 seconds to comply, failing to do so will receive both a leave buster (for AFK) and Ban strike on their account (assumeing third party bot software).
This kind of thing currently cannot be monitored or tracked on the current league client. Hopefully something like this implemented with the new one.