Just dodging every game there is a Vayne on my team.
People can say she's good or usable until you're blue in the face but I won't play with her, not when I'm 2-17 with her on our team during the season, and 9-1 against Vaynes.
I'm not good at League but I have a 55% win rate otherwise. Not worth the risk to play with the most toxic champ in the game that almost always feeds and AFKs if you're lucky.