The effect Yuumi could have on juggernauts:
Imagine a darius, a morde, an aatrox with Yuumi. You have these juggernauts that don't have tools to engage then you equip them with an invulnerable character stacked with engage tools that boost their damage. I think we might see a meta change, at least at the pro level, revolving around Yuumi... or she'll be permabanned.
Vladimir as an example. Vlad is untargetable when he uses his blood pool ability. However, he can still take damage, and any lock-ons will remain locked on until the ability, effect, or channel is completed or interrupted. Yuumi will still be entirely vulnerable to AoE attacks, and things like Cait's ultimate or Fidd's drain. The hard counter here, I think, will be champs who excel at doing large amounts of AoE damage, like Ahri, Anivia, or even Singed.
or particularly
, broken and top-tier as she already is - more so than juggernauts. I'm not saying you won't see pros possibly picking
to synergize with her, but I'd be surprised if she fully breaks the meta; however, I've been wrong before. A lot will probably depend on how strong her ult is.