It just depends on champions. Some champs can abuse runes better than others and other champs would find the same rune useless.
Cheap shot for example imo is garbage on Ahri.
Because the cooldown of it is 4 seconds, and her charm is 12 seconds without any cdr so by the time you even proc it 1 time some other champ could have easily proc it 2-3 times already. Charm is the only movement impairing effect in her kit and it's a single target skillshot that will get blocked by minions so it's even harder to abuse during laning phase. Oh and her charm cost 85 Mana at all ranks so you will just run out of mana for using it 2 times.