Arcane vs Low sustain melees to wear them down with you're W
PTA vs squishy melees to trade more effective early on. However, it's not as strong later on once you're second Q is mostly truedamage, since truedamage isn't affected by the 10% damage amp.
Electrocute vs squishys, especially ranged ones, to have a high all-in kill threat.
Conqueror vs tanks, though it has similar issues to PTA as her main damage later on already does truedamage and thus doesn't profit from the conversion. The bonus AD still is quite impactfull and it still helps out alot in the early-mid vs armor rush.
I personally also really like Fleet Foodwork vs strong poke or into some champs like Sion or Darius. Ever since it got buffed for melees to give full value from minions, it offers alot sustain in lane, and the extra mobillity helps alot at dodgeing stuff like sions Q, darius Q or disengageing after befor darius gets his passive stacked. It also helps you to stick on a target till the second Q is ready.
Glacial augment can also be strong to dominate good matchups, as it basically gurantees that you can fllow on your first q with a W and a second Q, and if paired with a randuins it can add alot extra utillity for engage later on. Though would only use it if i'm sure i can win trades without a combat keystone and if my team lacks a proper engage.
Dark Harvest is also a rune to watch in save matchups. doesn't do much in the lane, but her cleanup potential in mid-lategame fights gets massive with basically an more powerfull electrocute that resets on takedown and can be recharged by takeing a camp or cannon-minion
For Garen i'd either get fleet foodwork and play it save, the extra speed can help you disengageing from his spin, or go PTA and go for trades, just walk up for AA+Q and then E away duering his Q animation, and then you can E back onto him for AA+Q2 and then walk off.
VS Darius, either commet as he lacks sustain as long as you avoid his Q, or fleet foodwork so you can more easily avoid the Q-blade in trades and out sustain him in between trades, also helps you playing it save should you fall behind. don't try to go for extendet trrades vs his passive, at max get of the second Q and then get away from him.
too)_ but you really don't do enough damage to a lot of tanks in the laning phase and it will be even harder after some of the buffs they got. Taking 
because you're definitely going to lose the trade damage-wise and when you take Klepto you're not trying to win lane as hard.
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##On any champion, always try to make trades again Darius as short and as effective as possible. Extended fights against Darius is how you int.
