This game could benefit from adapting the Protoss Disruptor's attack from SC2
Disruptors are such a good micro-intensive unit for Starcraft 2. If you're not paying attention to those Purification Novas coming your way, you could lose a massive portion of your Marine/Marauder ball in an instant. OUCH.
Now what if a similar ability were in League? IIRC, Viktor's ultimate is the only thing that comes close right now. But would something with this kind of gameplay be fun to fight against?