(in-game bug)

Tried to play league today but wasnt able to, got in game and guess the whole thing was bugged. I couldnt use my mouse(was a normal cursor rather than the glove) or keyboard or anything i couldnt even alt-f4 only thing that worked was Alt-tabbut had to open task manager to close it, not a single button worked in game. I've done everything i can think of to try to fix this but i haven't fixed the problem yet. Any help would be appreciated.