I've been playing a lot of Vlad since the rework, here's what I can share:
Current Vlad relies a lot more on CDR to keep up his damage and healing, since E can totally kill you if you're not careful and Q is the most consistent way of topping yourself off, not to mention having your W and R much more often. For this reason I always play him on mid, where his matchups are much more even than in top and most of them are actually in your favor (I've seen plenty of people grabbing
to counter me, Vlad right now roflstomps Fizz), and since mid lane is packed with AP champs you can rush your new favourite item:
, which acts as a surrogate Will of the Ancients, it simply has everything you need. After that grab
and
and then finish
, and with scaling CDR runes you're all set, you can spam your spells as much as you like, with a heavier emphasis on Q in order to not kill yourself as previously stated. Protobelt is an underrated item that, just like SV, gives Vlad all he wants, and even has a short range dash/shotgun to finish off people or hit better ults. Many times I've had the highest champion damage in my team with those two items alone.
After those, it's your choice. I almost always rush
and
to maximize your damage and keep people at an arm's reach for yourself and your team, and for your last item it depends on what the enemy is building. I find
to be an excellent purchase that synergizes with your Rylai and your passive, and allows you to shred health stackers; if the enemy has heavy MR, I suggest you get
instead, much cheaper and chews through their defenses.
So yes, bigger emphasis on HP than old Vlad, since your E scales with the thing, but AP is equally as important in order to maximize your healing potential and not kill yourself in fights.
I differ from most of the people in this forum, I actually think Vlad got a lot better since the rework, your damage potential is through the roof and you're actually a pretty decent lane bully in a lot of matchups, which translates into massive teamfight power later in the game, you just need to be a lot more careful and not spam your E as it can and will drain your entire HP if you're careless with it, use your Q much more frequently since with all your CDR it should be on a negligible CD, don't forget to use your ult on as many people as you can and watch your HP bar restore to full after it's finished. Use your W carefully as it drains a lot of your HP (which you can gain back with the damage it deals, btw), but with enough CDR it should be up in no time as well. I don't really think Vlad is as clunky as everyone makes him out to be, with reasonable management of your HP and your healing spells you should be dealing massive damage and healing yourself like it's nobody's business.