Mobility Growth & skill-shot stagnation
Skillshots.
Most champions have them, and their impact, or misplacement tends to determine success or failure. Skillful use of those skill-shots, it would seem, then; would be the primarily determining factor of success with the overwhelming majority of skillshot users.
While the correlation is certainly there, is it direct? Not every champ is overly reliant on skillshot placement, and there isn't even necessarily a correlation between reward and mechanical skill? Ever been completely wrecked by a point and click ability? Ever got out of the way of a deadly skill shot by accident? A well placed skillshot might not even be as effective as another point-and-click ability.
While most of these inconsistencies open up a large and varied set of challenges; that don't necessarily allow for a balancing change; there is one issue that represents a gamewide decay of the efficacy of skillshots & the reward vs effort ratio therein.
It is long overdue that: many skillshots be re-evaluated for their late-game vs early game effort required and those with a high disparity gain improvements in missile speed, activation speed, &/or width at high champion level
Not all skillshots necessarily need this treatment but some have such anemic speed & or width that they become significantly less useful &/or require far more effort against a mobile champion once their other-bonus-movement speed items come online.
Ivern's Rootcaller, for example, is one of the epitomal examples of a skillshot that goes from "slow" to "uselessly slow" in the late game with enemy champions being able to outrun it without sidestepping.
All champions will gain increasing movement speed over the course of a game through the sequential purchase and upgrade of boots. Most champions will gain more mobility through a combination of cooldown reduction and innate lowered timers on mobility skills. The net effect of this? All skillshots become harder to connect as any match progresses. This is how it is, how it has always been: but is it a good thing?
This feels like oversight. There is no reason for all skillshots to diminish in efficacy over the natural progression of every match. I'm not advocating every skillshot in the game receive a level 18 improved version, but there are certainly those that deserve a modest improvement in their level 18 mechanics to make the effort-required-to-hit less of an uphill battle over the course of a match.